© 2018 Triangle Biotechnology, Inc.  All rights reserved.

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RapidShear™ for Genomic DNA

Add RapidShear™​ reagent immediately before sonicating samples for faster fragmentation and better consistency.

Formulated specifically for the fragmentation of DNA. 

For Research Use Only. Not for use in diagnostic procedures.

See publication for more information:

Cavitation Enhancing Nanodroplets Mediate Efficient DNA Fragmentation in a Bench Top Ultrasonic Water Bath

Kasoji SK, Pattenden SG, Malc EP, Jayakody CN, Tsuruta JK, Mieczkowski PA, et al. (2015). PLoS ONE 10(7): e0133014. https://doi.org/10.1371/journal.pone.0133014

MegaShear™ for Chromatin

Add MegaShear™ reagent immediately before sonicating samples to rapidly and consistently extract and fragment chromatin for epigenetic assays.

Formulated specifically for the extraction and fragmentation of chromatin. 

For Research Use Only. Not for use in diagnostic procedures.

See publication for more information:

Cavitation Enhancement Increases the Efficiency and Consistency of Chromatin Fragmentation from Fixed Cells for Downstream Quantitative Applications

Anna M. Chiarella, Austin L. Quimby, Marjan Mehrab-Mohseni, Brian Velasco, Sandeep K. Kasoji, Ian J. Davis, Paul A. Dayton, Nathaniel A. Hathaway, and Samantha G. Pattenden. Biochemistry Article ASAP. DOI: 10.1021/acs.biochem.8b00075